Past Projects
If you are an investigator interested in accessing the data sets and study instruments from our past projects, please contact our team here.
The following studies have data from individual participants pertaining to their mood and behavior
Clinical Studies
ADAPT
SBIR Phase 1
Key Personnel: Derrick Hull (Talkspace), Pat Arean, Mike Pullmann, Patrick Heagerty, Brittany Mosser, Isabell Griffith Fillipo, Shiyu Chen
Randomized clinical trial to determine the best incentive model for retaining participants in a 12-week longitudinal SMART.
Participants randomized to:
Incentive arm: Low money with feedback or High money only
Treatment arm: Message-based psychotherapy or Weekly videoconferencing therapy
Talkspace
SBIR Pilot Study
Key Personnel: Derrick Hull (Talkspace), Pat Arean, Mike Pullmann, Ryan Allred, Shiyu Chen
Pilot study to determine feasibility of conducting a 12 week, fully remote randomized clinical trial.
Participants randomized to:
Message-based psychotherapy
Weekly, telephone/video-based psychotherapy
Engage
Key Personnel: Pat Arean, Patrick Raue, George Alexopoulos (Cornell)
Publications/Products
Alexopoulos, G. S., Raue, P. J., Banerjee, S., Marino, P., Renn, B. N., Solomonov, N., Adeagbo, A., Sirey, J. A., Hull, T. D., Kiosses, D. N., Mauer, E., & Areán, P. A. (2020). Comparing the streamlined psychotherapy "Engage" with problem-solving therapy in late-life major depression. A randomized clinical trial. Molecular psychiatry, 10.1038/s41380-020-0832-3. Advance online publication. https://doi.org/10.1038/s41380-020-0832-3
E. Agapie, S.A. Munson, G. Hsieh, P. Arean. “Understanding Clinician Needs in Using an Evidence-based Psychosocial Intervention.” CHI 2020: Workshop on Technology Ecosystems: Rethinking Resources for Mental Health
E. Agapie, C. Thompson, J.G. Carr, D Ferguson, G. Hsieh, S.A. Munson, P. Arean. “Clinician Reported Challenges in the Creation of Action Plans.” Society for Behavioral Medicine (SBM) 2020
Randomized clinical trial to
Compare efficacy of Engage to PST
Study the mechanism of action of Engage; and
Examine whether community-based clinicians can achieve and retain competence in Engage
Engage-T Pilot
Key Personnel: Pat Arean, Patrick Raue, Mike Pullmann, Trevor Cohen, Derrick Hull (Talkspace), George Alexopoulos (Cornell)
Publications/Products
Burkhardt, H. A., Alexopoulos, G. S., Pullmann, M. D., Hull, T. D., Areán, P. A., & Cohen, T. (2021). Behavioral Activation and Depression Symptomatology: Longitudinal Assessment of Linguistic Indicators in Text-Based Therapy Sessions. Journal of medical Internet research, 23(7), e28244. https://doi.org/10.2196/28244
Pilot study to evaluate the effectiveness of Engage when delivered via text-messaging using the Talkspace platform
All participants received Engage-T. Historical data from Engage R01 and Talkspace usual care data available as comparators.
HIPPOCRATIC App (DARPA)
Key Personnel: Pat Arean, Brittany Mosser, Isabell Griffith-Fillipo, Molly Woerner
Publications/Products
Bracken, Poctozny-Jones, Wolcott, Raffaele, Woodward, Gogel, Kiourtis, Schulte, Arean, Farry (Charles River, Tozny, Kryptowire, UW). Development of Human-Out-of-the-Loop Participant Recruitment, Data Collection, Data Handling, and Participant Management System. Human Factors and Ergonomics (HFES) Annual Conference 2020
Bracken, Wolcott, Potoczny-Jones, Mosser, Fillipo, Arean (Charles River, Tozny, UW). Detection and Remediation of Malicious Actors for Studies Involving Remote Data Collection. Joint conference on biomedical engineering systems and technologies (Biostec)
Large scale, fully remote study to determine if sensors from smartphones can predict cold, flu, (COVID), and incidence of TBI.
12-week study with daily EMAs and passive smartphone sensors
Ilios/GOLD
Key Personnel: Pat Arean, Joaquin Anguera (UCSF), Faith Gunning (Cornell)
Randomized clinical trial to:
Explore the effect of psychotherapy on CCN activation in patients with late-life depression;
Explore the effect that a plasticity intervention has on CCN activation, mood, and disability on patients with LLD; and
.Explore the relationship between CCN activation and depression & disability outcomes
Participants randomized to:
EVO
WORDS
Problem Solving Therapy
Publications/Products
Anguera, J. A., Gunning, F. M., & Areán, P. A. (2017). Improving late life depression and cognitive control through the use of therapeutic video game technology: A proof-of-concept randomized trial. Depression and anxiety, 34(6), 508–517. https://doi.org/10.1002/da.22588
Mobile Mental Health Apps for Essential Workers and Unemployed during COVID-19
Key Personnel: Kate Comtois, Pat Arean, Mike Pullmann, Felicia Mata-Greve, Brittany Mosser, Morgan Johnson
Study to determine acceptability, feasibility, usability, and effectiveness of mobile mental health apps for addressing risk factors associated with suicide risk in essential workers and unemployed individuals during COVID-19
Participants randomized to use one of the following for 4 weeks:
7 Cups of Tea
Beautiful Mood
Calm
COVID Coach
Publications/Products
Mata-Greve, F., Johnson, M., Pullmann, M. D., Friedman, E. C., Griffith Fillipo, I., Comtois, K. A., & Arean, P. (2021). Mental Health and the Perceived Usability of Digital Mental Health Tools Among Essential Workers and People Unemployed Due to COVID-19: Cross-sectional Survey Study. JMIR mental health, 8(8), e28360. https://doi.org/10.2196/28360
Patient Activation
Pilot Study
Key Personnel: Pat Arean, Patrick Raue, Brenna Renn, Nichole Sams
Pilot study to test the feasibility and acceptability of a low-intensity psychosocial intervention for mild-to-moderate depression delivered by non-expert behavioral health technicians
Stay Connected: COVID-19 Older Adults Needs Assessment
Key Personnel: Pat Arean, Nichole Sams, CREATIV
Survey of older adults about the impact of social isolation as a result of COVID-19 on mental health and well-being
Survey distributed locally and nationally
Publications/Products
Sams, N., Fisher, D. M., Mata-Greve, F., Johnson, M., Pullmann, M. D., Raue, P. J., Renn, B. N., Duffy, J., Darnell, D., Fillipo, I. G., Allred, R., Huynh, K., Friedman, E., & Areán, P. A. (2021). Understanding Psychological Distress and Protective Factors Amongst Older Adults During the COVID-19 Pandemic. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 29(9), 881–894. https://doi.org/10.1016/j.jagp.2021.03.005
TRY Study
Key Personnel: Pat Arean, Jessica Jenness
Pilot study to determine whether a neuroscience-inspired cognitive remediation video game (EVO) that targets the cognitive control network will improve executive functioning and resilience to psychiatric symptoms in typically developing 6th grade students
ITS
UWAC R34 001
Key Personnel: Pat Arean, Patrick Raue, Brenna Renn, Emily Friedman, Zoran Popovic, Ryan Allred
Co-design Intelligent Tutoring System (ITS) with students from Heritage University, a subset of whom them used telephone-based CBT with patient participants
Pilot with Appalachia State University, Azusa Pacific University, and USC evaluating BA level social work students who were randomized to use ITS as part of their coursework as compared to classmates that received control materials
Publications/Products
Renn, B. N., Areán, P. A., Raue, P. J., Aisenberg, E., Friedman, E. C., & Popović, Z. (2021). Modernizing Training in Psychotherapy Competencies With Adaptive Learning Systems: Proof of Concept. Research on social work practice, 31(1), 90–100. https://doi.org/10.1177/1049731520964854
Aisenberg. E., O’Brien, M., Hodge, C., & Juarez, M. (May 2020). “Nueva Vista—Paraprofessionals delivering telephone based CBT for depressed rural Latinx.” Latino Social Work Organization National Conference. Portland, OR.
Montana
UWAC R34 002
Key Personnel: Pat Arean, Deb Kaysen (Stanford), Emily Friedman, Ryan Allred
Utilized DDBT methodology to redesign task-sharing model of BA with case managers and licensed mental health providers in Montana
Survey Data
The following studies are survey studies, primarily one-time engagements with participants.
Adaptations to Psychological First Aid (PFA)
Key Personnel: Deb Kaysen (Stanford), Pat Arean, Patricia Watson (National Centers for PTSD), Brittany Mosser, Mike Pullmann, Jed Jacobsen
Objective was to learn how PFA has been adopted and adapted across the US to address the mental health needs of health care workers during COVID-19, as well as usability challenges with PFA
Citizen Science
Key Personnel: Pat Arean, Brittany Mosser, Felicia Mata-Greve
Survey to learn about individuals' thoughts on Citizen Science and online research communities as it relates to health sciences for big data science
Cold, Flu, & COVID Attitudes
Key Personnel: Pat Arean, Brittany Mosser, Isabell Griffith Fillipo, Shiyu Chen
Survey to learn about individuals' attitudes related to public health activities around cold, flu, COVID and willingness to participate in remote research
Used as recruitment tool for HIPPOCRATIC App Study
Consumer Opinions Regarding Online vs In-Person Psychotherapy
Publications/Products
Renn, B. N., Hoeft, T. J., Lee, H. S., Bauer, A. M., & Areán, P. A. (2019). Preference for in-person psychotherapy versus digital psychotherapy options for depression: survey of adults in the U.S. NPJ digital medicine, 2, 6. https://doi.org/10.1038/s41746-019-0077-1
Two surveys in late 2016/early 2017 asking consumers for their opinion about online versus in-person psychotherapy
Key Personnel: Pat Arean, Brenna Renn
Facebook – Cambridge Analytica
Key Personnel: Pat Arean, Abhi Pratap, Ryan Allred, Brenna Renn
Publications/Products
Pratap, A., Allred, R., Duffy, J., Rivera, D., Lee, H. S., Renn, B. N., & Areán, P. A. (2019). Contemporary Views of Research Participant Willingness to Participate and Share Digital Data in Biomedical Research. JAMA network open, 2(11), e1915717. https://doi.org/10.1001/jamanetworkopen.2019.15717
Survey to learn about consumer opinions regarding their willingness to participate in online research in light of Facebook/Cambridge Analytica medica coverage and their opinions may change over time
Fitness, Wellness, & Mental Health Apps Attitudes
Key Personnel: Pat Arean, Brittany Mosser, Isabell Griffith Fillipo, Shiyu Chen
Survey to learn about individuals' attitudes related to using fitness, wellness, and mental health apps and willingness to participate in remote research
Used as recruitment tool for HIPPOCRATIC App Study
Kaiser Provider Survey
Survey of mental health providers and/or providers primarily involved in mental health treatment in primary care medicine to determine:
If mental health clinicians see a value in obtaining information from people's smartphones that could inform treatment decisions, and
The best mode of delivery for that information
Key Personnel: Pat Arean
Publications/Products
Areán, P. A., Friedman, E. C., Pratap, A., Allred, R., Duffy, J., Gille, S., Reetz, S., Keast, E., & Clarke, G. (2021). Using Real-world Data for Decision Support: Recommendations from a Primary Care Provider Survey. The Permanente journal, 25, 10.7812/TPP/20.213. https://doi.org/10.7812/TPP/20.213
Mobile Mental Health Apps for Essential Workers and Unemployed during COVID-19
Study to determine acceptability, feasibility, usability, and effectiveness of mobile mental health apps for addressing risk factors associated with suicide risk in essential workers and unemployed individuals during COVID-19
Participants randomized to use one of the following for 4 weeks:
7 Cups of Tea
Beautiful Mood
Calm
COVID Coach
Key Personnel: Kate Comtois, Pat Arean, Mike Pullmann, Felicia Mata-Greve, Brittany Mosser, Morgan Johnson
Publications/Products
Mata-Greve, F., Johnson, M., Pullmann, M. D., Friedman, E. C., Griffith Fillipo, I., Comtois, K. A., & Arean, P. (2021). Mental Health and the Perceived Usability of Digital Mental Health Tools Among Essential Workers and People Unemployed Due to COVID-19: Cross-sectional Survey Study. JMIR mental health, 8(8), e28360. https://doi.org/10.2196/28360
Q-RFA: Measuring Psychotherapy Quality
Key Personnel: Pat Arean, Brenna Renn, Ryan Allred
Surveys of mental health providers and patients (separately) to learn more about reactions to methods for measuring psychotherapy quality
Publications/Products
Renn, B. N., Allred, R., Rivera, D., Fisher, D., Mosser, B. A., Duffy, J., Stephens, K. A., & Areán, P. A. (under review). A mixed methods examination of provider perspectives on psychotherapy quality measures. Psychological Services.
Stay Connected Provider Survey
Survey of providers trained in Stay Connected by AIMS Center about the acceptability, appropriateness, and feasibility of the intervention
Key Personnel: Patrick Raue
Stay Connected: COVID-19 Older Adults Needs Assessment
Key Personnel: Pat Arean, Nichole Sams, CREATIV
Survey of older adults about the impact of social isolation as a result of COVID-19 on mental health and well-being
Survey distributed locally and nationally
Publications/Products
Sams, N., Fisher, D. M., Mata-Greve, F., Johnson, M., Pullmann, M. D., Raue, P. J., Renn, B. N., Duffy, J., Darnell, D., Fillipo, I. G., Allred, R., Huynh, K., Friedman, E., & Areán, P. A. (2021). Understanding Psychological Distress and Protective Factors Amongst Older Adults During the COVID-19 Pandemic. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 29(9), 881–894. https://doi.org/10.1016/j.jagp.2021.03.005
Subject Incentives Survey
Survey to learn what payment methods people prefer for their participation in online research studies
Key Personnel: Pat Arean
Passive Data
HIPPOCRATIC App (DARPA)
Key Personnel: Pat Arean, Brittany Mosser, Isabell Griffith-Fillipo, Molly Woerner
Publications/Products
Bracken, Poctozny-Jones, Wolcott, Raffaele, Woodward, Gogel, Kiourtis, Schulte, Arean, Farry (Charles River, Tozny, Kryptowire, UW). Development of Human-Out-of-the-Loop Participant Recruitment, Data Collection, Data Handling, and Participant Management System. Human Factors and Ergonomics (HFES) Annual Conference 2020
Bracken, Wolcott, Potoczny-Jones, Mosser, Fillipo, Arean (Charles River, Tozny, UW). Detection and Remediation of Malicious Actors for Studies Involving Remote Data Collection. Joint conference on biomedical engineering systems and technologies (Biostec)
Large scale, fully remote study to determine if sensors from smartphones can predict cold, flu, (COVID), and incidence of TBI.
12-week study with daily EMAs and passive smartphone sensors